The solipsist, on the analogy of our dream-experience, imagines a higher mode of selfhood or spirit to whom the world is like a dream; his own self is a lower or deluded mode of this selfhood and to it the world appears as real. Thus objectivity appearing to the lower self is illusory and contingent, not ultimate. This analogical argument for a higher self, as against an alien God, has this counter-argument. In dreams I have unpleasant experiences because of certain (...) external causes, such as physiological and psychological. But what compels my higher self to have the unpleasant dreams that are my waking experiences of life? In other words, why cannot my higher self have nothing but rosy dreams when there cannot be anything else than itself to force on it bad ones? The answer to this is that in our dreams and fantasies we do not have unpleasant experiences due to external causes only, but also due to our inherent love of experience for its own sake. Our dreams are our wish-fulfilments too. We love to have all sorts of experiences, to taste all kinds and shades of emotion. Thirst for passions, curiosity after the unknown, and adventure for the strange and the new mark our empirical self. So it is not absurd to conceive the higher self fashioning its dreams, our waking experiences, as a mixture of pleasant and unpleasant elements rich in variety and complexity. And just as my empirical self is said to enjoy the experiences of my dreams, so this higher self may be said to enjoy his dreams, my waking experiences. (shrink)

Let us now examine one of these radical positions, say, the sceptical one first. According to this, since error is a fact, we may as well treat every perception as erroneous, only undetected so far and so accepted as true. But if we accept error as a fact we must also accept truth as such, for an error cannot be known as one unless we know something as true. When one says one mistook a rope for a snake one must (...) know the rope truly, otherwise there can be no mistake. One may think erroneously, "I am apparently seeing a rope but it may be that I am only imagining it, just as I imagined the snake; I may be mistaking something else for a rope." But then one must also see that as the rope is thus doubted, the unreality of the snake must also be doubted, for it is against the rope as real that the snake becomes unreal. And now one would have to say, "Perhaps I am imagining this rope which might really be the snake I thought I imagine." But in this state of oscillation one cannot pronounce any judgment at all, and so cannot assert anything about the truth and falsity of any perception. The original perception proving false leads one, through analogy, to doubt the latter perception. But if there is a doubt regarding the falsity of the original perception, there cannot be a legitimate doubt regarding the validity of the later one. More generally we may say that if one doubts one's perceptions of certain objects on the ground that some perceptions regarding these had proved false in the past, this doubt logically involves the possibility of those perceptions, rejected as false being true. So that though one may psychologically take up the attitude of doubt with respect to every perception, this attitude has no rational backing. If, however, one doubts certain objects of perception because some other perceptions e.g., snakes) proved false, one has only a weak analogy and is, moreover, forced to doubt all perceptions, including those which proved certain perceptions false, thereby starting the original doubt. But then the reasoning given above which will dispel this doubt will have to be applied. So that this doubt cannot be rationally justified. The argument that since certain perceptions have proved false therefore every one of them may prove so is, after all, a very weak one. A perception is false only when it is falsified by a true one, and we cannot doubt a perception unless it is so falsified. (shrink)

True Hinduism has a power and beauty that no one acquainted with it can regard with anything but the deepest respect. This book contains a range of scriptures, an array of ritualistic procedures and traditions of brahminical orthodoxy, varied interpretations coupled with multiple views. True Hinduism has a power and beauty that no one acquainted with it can regard with anything but the deepest respect. You have to approach it as you approach poetry, with a willing suspension of disbelief. Above (...) all the peripheral myths, customs, beliefs and rites, rises the great. (shrink)

The National Blood Policy in India relies heavily on voluntary blood donors, as they are usually assumed to be associated with low levels of transfusion-transmitted infections . In India, it is mandatory to test every unit of blood collected for hepatitis B, hepatitis C, HIV/AIDS, syphilis and malaria. Donors come to the blood bank with altruistic intentions. If donors test positive to any of the five infections, their blood is discarded. Although the blood policy advocates disclosure of TTI status, donors (...) are not, in practice, informed about their results. The onus is on the donor to contact the blood bank. Out of approximately 16 000 donations in the past 2 years, 438 tested positive for TTI, including 107 for HIV. Only 20% of the donors contacted the blood bank; none of them were HIV positive. Disclosure by blood banks of TTI status by telephone or mail has resulted in serious consequences for some donors. Health providers face an ethical dilemma, in the absence of proper mechanisms in place for disclosure of test results, regarding notification to donors who may test positive but remain ignorant of their TTI status. Given the high cost of neglecting to notify infected donors, the authors strongly recommend the use of rapid tests before collecting blood, instead of the current practice, which takes 3 h to obtain results, and disclosure of results directly to the donor by a counsellor, to avoid dropouts and to ensure confidentiality. (shrink)

The development of action representation during adolescence was investigated using a visually guided pointing motor task to test motor imagery. Forty adolescents and 33 adults were instructed to both execute and imagine hand movements from a starting point to a target of varying size. Reaction time was measured for both Execution and Imagery conditions. There is typically a close association between time taken to execute and image actions in adults because action execution and action simulation rely on overlapping neural circuitry. (...) Further, representations of actions are governed by the same speed-accuracy trade-off as real actions, as expressed by Fitts’ Law. In the current study, performance on the VGPT in both adolescents and adults conformed to Fitts’ Law in E and I conditions. However, the strength of association between E and I significantly increased with age, reflecting a refinement in action representation between adolescence and adulthood. (shrink)

Recent advances in genomic and imaging techniques have revealed the complex manner of organizing billions of base pairs of DNA necessary for maintaining their functionality and ensuring the proper expression of genetic information. The SMC proteins and cohesin complex primarily contribute to forming higher‐order chromatin structures, such as chromosomal territories, compartments, topologically associating domains (TADs) and chromatin loops anchored by CCCTC‐binding factor (CTCF) protein or other genome organizers. Cohesin plays a fundamental role in chromatin organization, gene expression and regulation. This (...) review aims to describe the current understanding of the dynamic nature of the cohesin‐DNA complex and its dependence on cohesin for genome maintenance. We discuss the current 3C technique and numerous bioinformatics pipelines used to comprehend structural genomics and epigenetics focusing on the analysis of Cohesin‐centred interactions. We also incorporate our present comprehension of Loop Extrusion (LE) and insights from stochastic modelling. (shrink)

In developed economies, powerful legislative and regulatory frameworks, for people with disability over the last five decades, have provided major motivation for business compliance with disability in the workplaces. However, developing economy like India is marked by emergent disability legislation, weak institutional enforcement and an evolving disability rights movement. In the absence of strong institutional expectations, the private sector’s role in mainstreaming the disability agenda has been largely an act of voluntary participation. Drawing upon an in-depth, multilevel, cross-functional qualitative study (...) of four Indian information technology sector companies, this paper explores why these companies engage in pro-social corporate behaviour in favour of disability. The study locates itself in the context of conceptualization of PWD as employee stakeholders and the literature on strategic CSR. The findings reveal that strategic factors promote voluntary business engagement with disability at workplaces and contribute to understanding of workplace integration of minority employees. (shrink)

This paper contains two traditions of diagrammatic studies namely one, the Euler–Venn–Peirce diagram and the other, following tradition of Aristotle, the square of oppositions. We put together both the traditions to study representations of singular propositions, their negations and the inter relationship between the two. Along with classical negation we have incorporated negation of another kind viz. absence. We have also considered the changes that take place in the context of open universe.

An examination of seventeenth- and eighteenth-century French history indicates that the relationship between the Jesuits and Quietism was shaped by politics as well as by concerns of theological orthodoxy. During the late 1690s, the Jesuits championed François Fénelon accused of Quietism at the same time as they spearheaded an attack against Quietism in Burgundy, emphasizing crimes of spiritual incest or the abuse of clerical authority. Such ambiguity indicates that the Jesuits were motivated by a desire to consolidate political power in (...) Louis XIV... trades court. However, the fusion of Quietist heresy, charges of spiritual incest, and political gamesmanship would ultimately make the Jesuits themselves vulnerable to claims of heresy and abuse when the Girard/Cadière affair became a national scandal in 1731. This essay argues that this disquiet over clerical behavior and power was articulated in a changing political culture between the late seventeenth century and the 1730s. Growing dissatisfaction against the crown established a new political consciousness, one that regarded the politics of secrecy as problematic if not outright illegitimate. The secrecy of the confession, the emphasis on interiority seemingly at the expense of morality, and the enigmatic language of mysticism, all associated with Quietism played into fears of clerical (or “Jesuit”) cabal and conspiracy. When Jesuit opponents linked the order to Quietism, they presented the Jesuits as threats to an emerging set of political values in which legitimate authority was transparent and open while illegitimate power operated in the shadows. (shrink)

BackgroundAdverse Childhood Experiences have been associated with long-term physical and mental health conditions, toxic stress levels, developing unstable interpersonal relationships, and substance use disorders due to unresolved childhood adversities.AimsThis study assessed the perspectives of mental health providers regarding their adult patients’ coping with ACEs during COVID-19 in Houston, Texas. Specifically, we explored how individuals with ACEs are coping with the increased stresses of the pandemic, how MHPs may provide therapeutic support for individuals with ACEs during this pandemic, pandemic-related challenges of (...) accessing and utilizing mental health services for individuals with ACEs, and the awareness and treatment of ACEs among MHPs.MethodsTen in-depth semi-structured virtual interviews were conducted with licensed MHPs from November 2021 to April 2022 in Houston, Texas. Interviews were coded and analyzed for emerging themes through an inductive open coding approach to discover insights regarding coping with ACEs during COVID-19.ResultsFour key themes experienced by individuals with ACEs emerged from the MHP interviews: Maladaptive emotional dissonance and coping outlets during the pandemic, Difficulties with social connectedness and significance of social support, Heightened daily life stressors and coping with the ongoing disruption of the pandemic, and Changing interactions with the mental health system. Themes from this study highlighted that resilience, seeking treatment, and strong social support can help develop healthy coping strategies among individuals with ACEs.ConclusionThis study may help inform best clinical practices to develop interventions and policies regarding ACEs such as a resilience-promotion approach that targets all the socio-ecological levels. In addition, findings highlight the synergy of psychotherapeutic and pharmacological management via tele-health modalities, in helping individuals with ACEs continue receiving the care they deserve and need during a persistent pandemic and an uncertain future. (shrink)

This handbook provides a comprehensive overview of Islamic ethical issues within a wide spectrum of philosophy of science topics, examining the development of the model of moral inclusiveness in economics, science and society from ontological, epistemological and analytical perspectives. This paradigm takes the view that ethics is systemically endogenous, and can be studied by the most rigorous scientific analysis pertaining to diverse issues and problems of ethicality in socio-scientific inquiry. This handbook takes a sweeping transdisciplinary approach that is deeply phenomenological, (...) to the nature and logic of scientific inquiry of, and in, the Qur’an. Such an approach invokes the episteme of the unity of knowledge in the socio-scientific systemic sense. The volumes' respective sections focus on the nature, logic, and role that ethics plays in formulating new vistas of alternative epistemic futures in Islamic economics, finance, and the social sciences. The ideas presented are situated within the broader context of the post-modernist, post-pandemic, and the post-Covid-19 epoch, while being aimed at conceptualising a distinctive new outlook of transdisciplinary intellection in Islamic philosophy. The content is rigorously conceptual, qualitative, quantitative, and applied. Covering a diversity of subject areas from philosophy of science, to economics and in socio-scientific context within the realm of Islamic philosophy, this forms a key text for scholars in these respective arenas, led by pioneering scholarship in Islamic studies. (shrink)

The field of information technology is broadened up to the domain of ‘learning’ systems and cybernetics. In covering this extension of the field due recourse is made to the epistemological basis of theory construction. When so comprehended, information technology becomes a philosophical inquiry on a variety of social, scientific and technological issues. A new idea that we refer to as neuro-cybernetics is born. The term neuro-cybernetics is used to delineate the epistemological field of system and cybernetic study. The above-mentioned phenomenological (...) or the epistemic model of a cybernetic and system type is applied to flood control problem in Bangladesh. This example presents an application of the cybernetic model to a physico-human problem. This is the nature of socio-scientific system. In it, organically unifying relations occur between the environment and the human world, with the objective of controlling the perennial problem of floods by using interactive factors. (shrink)

The question posed is whether the optimization methods of calculus that are often used in social and scientific analyses offer an appropriate analytical approach to analyze problems that are immersed in systemic complexity and its consequences. This paper refers to the portfolio of such complex problems belonging to social and scientific forces. We refer to such a complex combination by the term ‘socio-scientific’. In the study of socio-scientific complexity, dynamic preferences, intricate decisions, and uncertain behavior, endogenous relations and systemic perturbations (...) abound. The arguments presented in this paper establish that the methodological approach of optimization and steady-state equilibrium turns out to be nicety rather than objectivity in the presence of complexity. Complex situations of the socio-scientific universe cause perturbations in the variables; there explaining complexity formed by the social embedding of variables. Indeed, human individuals, institutions and governments, and society at large are complex interrelated entities. Therefore, complex interrelations caused by social embedding remain submerged in social perturbations. However, interactions arising from social embedding also generate endogenous and complex relations. The contribution of this paper is in the area of endogenous learning in the wellbeing objective criterion function. The interrelationships between the emergent cognitive variables now cause interactive embedding, complexity, and social perturbations. Yet such perturbations are not altogether uncontrollable. They can be and need to be controlled for the purposes of social explanation—hence demanding predictability—even as the complex nature of evolutionary systemic learning proceeds. The controllability problem of extreme perturbations leads us to formalize a mathematical methodology to study controllable perturbations while avoiding extreme forms of perturbations in socio-scientific theory. (shrink)

Three distinct models of political economy are articulated in this article to chart out the possible politico-economic futures of the Arab World. Of these, the present predicaments of the revolutionizing Arab populace are argued to have been caused by the continuance of the wrong social choices. It depended for a long time now on the alienating model of differentiation and alienation of the Arab nations by their rulers, and by their uncritical immersing in the equally debilitating globalization agenda. Two models (...) of the alienating and unfeasible types are formulated as the prevailing ones today. The arguments and empirical study of limited socioeconomic data with the examples of Egypt, Tunisia and Yemen, which are considered as exemplary of the revolutionary Arab World, point out that social factors based on the demand for participation and representation, self-reliant social change, and opportunities are the overwhelming factors of politico-economic change. These factors, as opposed to the purely economic factors, must be embedded in a synergistic way with the rest in a distinctive future model of Arab political economy. Three formal models of possible political economy of the future Arab World with their evolutionary futures are formalized. Necessary social and policy implications are drawn in reference to these three evolutionary Arab futures in political economy. (shrink)

Although current literature about the “cure versus care” issue tends to promote a patient-centered approach, the disease-centered approach remains the prevailing model in practice. The perceived dichotomy between the two approaches has created a barrier that could make it difficult for medical students and physicians to integrate psychosocial aspects of patient care into the prevailing disease-based model. This article examines the influence of the formal and hidden curricula on the perception of these two approaches and finds that the hidden curriculum (...) perpetuates the notion that “cure” and “care” based approaches are dichotomous despite significant changes in formal curricula that promote a more integrated approach. The authors argue that it is detrimental for clinicians to view the two approaches as oppositional rather than complementary and attempt to give recommendations on how the influence of the hidden curriculum can be reduced to get a both-cure-and-care-approach, rather than an either-cure-or-care-approach. (shrink)

Adolescent brain development has become an important target for governments to act upon, in the name of healthy individuals and economic prosperity. In the Foresight Project on Mental Capital and Wellbeing , initiated by the Government Office for Science, adolescent behaviour was identified as one of the key challenges for UK policy. The report draws on 'state of the art′ evidence from scientific experts, to recommend ways in which to 'capitalize′ on mental faculties to improve, boost, and make maximum use (...) of the cognitive resources and mental health of individuals during the entire lifespan. Specifically, through a close analysis of the category of adolescence in cognitive neuroscience, we examine the perspective of personhood espoused by MCW. We show how the notion of 'plasticity′, which underpins the recommendations about how to “make the most” of adolescents′ developing brains and cognitive resources, creates vital linkages between neuroscience and neosocial policy. (shrink)

This essay introduces the second installment of a symposium in Common Knowledge called “Apology for Quietism.” This introductory piece concerns the sociology of quietism and why, given the supposed quietude of quietists, there is such a thing at all. Dealing first with the “activist” Susan Sontag's attraction to the “quietist” Simone Weil, it then concentrates on the “activist” William Empson's attraction to the Buddha and to Buddhist quietism, with special reference to Empson's lost manuscript Asymmetry in Buddha Faces. The author, (...) who is also editor of the journal, argues against the effort of some contributors to substitute new terms for quietism and emphasizes instead what he calls “the need for repose.”. (shrink)